During an unexpected, deadly second wave of the coronavirus outbreak in New York City, two neighbors, Rachel and Lily, navigate life in quarantine. While Rachel juggles her many telemedicine clients as well as a shaky, passionless marriage, Lily is upstairs just trying to convince her Wall Street clientele that her very specific skillset is still just as valuable over video as it was in person.
While conducting telehealth appointments from her New York City brownstone, Rachel tends to one of her patients with an strange injury. Upstairs, Lily finds herself in a risky position with one of her clients.
Lily figures out what to do with her dangerous client. Rachel attempts to gather evidence from her various patients to present to her husband, who works at the CDC.
Rachel attempts to coax confidential CDC information from Zach. Lily tries to continue pursuing her career dreams despite the chaos.
Rachel continues to seek information regarding the virus, while also managing an alarming situation in Lily's life. Meanwhile, Zach is under scrutiny at the CDC.
Rachel enlists Lily's help with an important task in order to further her mother's medical research into a cure. Zach learns surprising information from his CDC colleague and former lover.
Racing against time, Rachel and Lily are forced to make a decision that could alter their lives in order to save humanity.
