Social worker Mark Lilly helps new citizens—both human and "other"—begin the process of adapting to life in the Big Apple, but his coworkers, demonic bureaucrat Twayne, drunken wizard Leonard Powers, surly law enforcement head Frank Grimes & his girlfriend, Callie, don't make it easy.
Twayne and Callie build a summer camp to cover up their raid on a wizard training ground.
Callie must care for her younger, hotter demon sister, who happens to be engaged to Twayne.
When his favorite TV series ends with a dumb twist, Grimes has a complete mental breakdown.
After being drafted into Satan's dark army, Twayne and Mark must do their patriotic duty and end the world.
Mark accidentally reactivates Leonard's magical arranged marriage.
Callie makes an evil Mark clone to compete in the DOI bowling league tournament.
Randall tries to make a quick buck on the Soul Exchange by selling off Mark's immortal soul.
Randall is infected by horrifying plants at sea when Twayne throws a cruise ship party.
Mark hooks up with an old girlfriend to test his open relationship.
Grimes' judgmental mother rises from the dead, and a neglected Randall reconsiders his living situation.
A Lilliputian arsonist escapes Mark's custody and finds an unlikely hiding place in Twayne's nose.
Randall's new arm lands him on the DOI's intramural football team, and Callie pimps out Leonard.
Twayne quits after getting roasted at his DOI 10-year anniversary party, leaving Mark in charge.
Callie is promptly promoted after turning into a man, causing strife in her relationship with Mark.
Lady Hoo-Ha, America's most adored pop star, goes zombie, and her many devoted fans follow suit.
A rabid Bat Boy takes a bite out of Mark, transforming him into New York City's latest superhero.
Callie's psychotic, prankster ex-boyfriend escapes from an asylum and wreaks havoc on Mark's life.
