Small for his age, Yukinari has been bullied and abused by girls all his life. Now in high school, he has developed a rare condition: whenever girls touch him, or even come close, he breaks out in hives. Imagine his surprise, when he is suddenly transported to the city of Seiren on a mystic world invisibly orbiting the Earth, and populated with vast numbers of women and very few men. Fortunately, he has a new friend, Miharu-chan, whose touch inexplicably doesn't affect him.
In an attempt to get close to Miharu, Fukuyama buys the school swimming pool, remodels it into a resort, and sends every boy but himself and (accidentally) Yukinari, tumbling out through a hole in the floor. And with the inadvertant help of Lisa's magic, he switches bodies with Yukinari.
An invitation to a baseball game turns out to be a trap set by Fukuyama. Blackmailed by him, Kirie is forced to fight in his all-girl kickboxing tournament.
Yukinari and Miharu finally go out on a date, with Fukuyama (and Kirie) in hot pursuit.
A fellow classmate of Yukinari and the others, Mamoru, appears as a cleaning superhero wanting to keep the school clean, confronting everyone that tries to litter. Miharu introduces him to Lilica, Fukuyama's maid, so that he learns how to do a better job.
Tomoka goes out to continue with her mission on getting a man for Maharu, but ends up keeping an eye for Kirie after she finds her dealing with some problems.
Miharu, Kirie, and Koyomi acquire a part time job at a video game convention in order to fix the bathtub (after being broken by one of Miharu's sneezing fits). When the forth part-timer fails to arrive, Yukinari is drafted into dressing up like a girl and playing eye-candy for a day.
To bring an end to Tomoka's boredom, Fukuyama starts a "unique" game of Mah-Jong involving dares and questionable clothing.
Everyone plays a part in a movie about three thief rabbit girls and two detectives. Fukuyama and Yukinari play as the detectives, and Miharu, Kirie, and Koyomi play as the rabbit girls. Lisa plays as a daughter and Mamoru as her father.
The school festival starts, oddly, at the same time that the portal to Seiren opens once again, sending a bewildered Maharu to Earth.
After a discussion involving Miharu's Seiko, Koyomi believes that she has spotted her father in the background of a news report, and begins to desperately search for him.
Miharu goes gift shopping for everyone while chaos breaks loose at Yukinari's house.
Miharu is taken back to Seiren by Ms. Kanata; Yukina's orders. Yukinari and the others prepare to go for her rescue.
Yukinari, Kirie, Tomoka, Lisa, and Maharu fight their way through to save Miharu from Yukina. At the end of the series, Yukinari, Miharu, Maharu, Kirie, Tomoka, Lisa, Fukuyama, Koyomi and Yukina all return to Earth and live happily ever after together.
