A soldier from the 15th century, a university student from the 19th century and a nurse from the present join the secret 'Department of Time', a secret department within the Spanish government with the ability to travel through time. Their mission is prevent changes in history.
The patrol is reunited after three years to investigate a debuting actor who looks exactly like Julián, who was believed to have been killed in action.
Alonso and Irene travel to the 1600s to the royal court of Philip IV. Meanwhile, Pacino and Lola must ensure that Pedro Almodóvar casts Antonio Banderas in his film "Labyrinth of Passion" in 1981.
As the patrol makes its way to England to prevent Elizabeth I from being murdered before ever being crowned queen, Amelia returns to the Ministry to help Julián.
Two teams are sent to 1937: Julian and Lola go to Madrid to investigate possible theft of Velazquez's Las Meninas. Pacino, Irene, and Velazquez go to Paris to ensure that Picasso paints Guernica.
After Lola is kidnapped, Pacino decides to alter the past to save her - but messing with the timeline comes at a high price.
When Albert Einstein is murdered in Madrid and his friend and fellow scientist Emilio Herrera is the prime suspect, Salvador takes matters into his own hands.
In 1832, King Ferdinand VII is being poisoned. The Ministry takes him to 2020 for medical treatment and replaces him with a stand-in, but they must ensure no one discovers the switch.
A dead body of a one-year-old is found near the Ministry's headquarters. As Salvador confesses to the crime, he offers an explanation by telling a tale of how Julian found himself in the year 2070.
